Disabling Microsoft AV in Win10

[hutch--]

Directly from my own up to date Win10.

How do I permanently disable Windows Defender in Windows 10 64 bit?
  How to Disable Microsoft Defender (Permanently)
  Click Start.
  Type "Windows Security" and click the option under "Best match".
  In the new window that opens, click Virus & threat protection.
  Under the Virus & threat protection heading, click Manage settings.
  Set the Tamper Protection toggle to the Off position.

Do things like his with extreme caution as you may leave your computer vulnerable. It should only be done on a win10 profile that is isolated from any other users and use another AV scanner that works on demand.

My choice is Kaspersky's KVRT.EXE that you download directly from Kaspersky.